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Status: Resolved Answers: 9 Is it safe to take 2 benadryl - Things You Didn’t Know https://www. Yahoo. If i take two benadryl pills (100mg) a couple hours after the caffeine pill AND smoke weed, what will the high be like? Should I induce - Answered by a verified Dog Veterinarian. Ask Dr. Otherwise, try a topical spray - like the kind used for sunburn which contain lidocaine. But a Baylor College of Medicine sleep expert cautions against turning to this type of medication as a sleep aid. I accidentally gave my dog 2 Benadryl pills. Namey on is it safe to take 2 benadryl: Depends on the dose of Benadryl (diphenhydramine). Unless you take 2 benadryls and 4 vicodins, that'll make for a fun night Benadryl (diphenhydramine) needs to be used with caution in those with the following conditions: glaucoma, BPH, urinary tract obstruction, asthma, hyperthyroidism, cardiovascular disease Apr 11, 2013 · If i took one caffeine pill (200mg) and then take two benadryl pills (100mg) and smoke weed? 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